Left Out in The Cold?

Mice left out in the cold: commentary on the phenotype of TRPM8-nulls

Detection of innocuous temperatures allows an organism to select an appropriate environmental climate, while the ability to recognize noxious temperature extremes warns of impending tissue damage. For temperatures considered cold, the menthol receptor TRPM8 is activated when temperatures drop below approximately 26 degrees C, thus making it an intriguing candidate as the molecular mediator of c...

Has Japan Been Left Out in the Cold by Regional Integration?

This research was done while I was a visiting scholar at the Institute for Monetary and Economic Studies (IMES) of the Bank of Japan (BOJ) during the spring of 2001. I am very grateful to the IMES and the BOJ for their hospitality and research resources, and would like to thank the seminar participants at the IMES, Hitotsubashi University, the Research Institute of Economy, Trade, and Industry,...

Left out of School Children in Rural and Tribal Areas: Causes and Ways of Remediation

  To identify the hurdles that 6 to 12-year-old children in rural and tribal areas face in going to school and ways of removing them a large sample of administrators, teachers, and students in the rural and tribal areas of Azerbaijan provinces was interviewed and given questionnaires with assumed validity and reliability of 0.70 through test-retest. Results show that three cultural, one p...

Lethargic mitochondria are left out

Lethargic mitochondria are left out he proper processing of a mitochondrial fusion protein called Mgm1 depends on sufficient ATP, based on results from Herlan et al. (page 167). Mgm1's energy dependence may ensure that tired mitochondria get left behind. Mgm1 can be found in the mitochondrial intermembrane space in two forms, the shorter of which (s-Mgm1) is generated by protease cleavage of th...

[Watch out for cold injuries now].